The chemical compatibilization of polyetheretherketone (PEEK) and polytetrafluoroethylene (PTFE) will result in a semi-crystalline thermoplastic polymer compound with a homogeneous and stable processing morphology. The compound exhibits improved impact strength and excellent tribological properties. The thermal and chemical resistance corresponds to the properties of the PEEK matrix material. The granules can be processed under the processing conditions of the matrix material by extrusion or injection molding.